Table 1.
Change of expression of genes related to meiotic resumption in oocytes following FSK and IBMX treatment.
| Feature ID | Annotations - database object name | Experiment –fold change* (original values) | Kal’s Z-test: P-value correction | Number of mapped reads before FSK and IBMX treatment | Number of mapped reads after FSK and IBMX treatment | Change of gene expression |
|---|---|---|---|---|---|---|
| WEE1 | WEE1 G2 checkpoint kinase | 9.7692308 | 0 | 13 | 127 | upregulated |
| H2AFY2 | Histone H2A (macroH2A2) | 8 | 0.006904653 | 2 | 16 | upregulated |
| H2AFY | Histone H2A (macroH2A1) | 1.2139303 | 0.010222819 | 603 | 732 | upregulated |
| ARPP19 | cAMP-regulated phosphoprotein 19 | 1.2087407 | 2.60E-06 | 1,739 | 2,102 | upregulated |
| CKS1B | Cyclin-dependent kinase regulatory subunit 1 | 1.1900074 | 0 | 8,126 | 9,670 | upregulated |
| PTTG1 | Securin | 1.1384134 | 0 | 37,099 | 42,234 | upregulated |
| CDK1 | Cyclin-dependent kinase 1 | 1.1268339 | 0.006824813 | 2,113 | 2,381 | upregulated |
| RB1 | Retinoblastoma-associated protein | 1.0946502 | 0.853703543 | 243 | 266 | unchanged |
| CDC5L | Cell division cycle 5-like protein | 1.0925637 | 0.136283354 | 1,923 | 2,101 | unchanged |
| CCNB2 | G2/mitotic-specific cyclin-B2 | 1.088404 | 3.04E-05 | 10,633 | 11,573 | upregulated |
| CDC25C | M-phase inducer phosphatase 3 | 1.0860763 | 0.000989742 | 7,656 | 8,315 | upregulated |
| C-MOS | Proto-oncogene serine/threonine-protein kinase mos | 1.0601145 | 0.006690682 | 15,720 | 16,665 | upregulated |
| ENSA | Alpha-endosulfine | 1.0523823 | 0.123577445 | 10,767 | 11,331 | unchanged |
| CCNB1 | G2/mitotic-specific cyclin-B1 | 1.0378686 | 0.428368701 | 17,772 | 18,445 | unchanged |
| MASTL | Serine/threonine-protein kinase greatwall | 1.0317363 | 1 | 3,277 | 3,381 | unchanged |
| CDC25A | M-phase inducer phosphatase 1 | −1.0940605 | 3.20E-07 | 5,176 | 4,731 | downregulated |
| PKMYT1 | Protein kinase, membrane-associated tyrosine/threonine 1 | −1.1303 | 0.0007733 | 1,535 | 1,358 | downregulated |
| CDC25B | M-phase inducer phosphatase 2 | −1.1393222 | 0 | 9,715 | 8,527 | downregulated |
*When the ratio is less than 1, it is converted to its negative inverse.
The transcriptome data have been deposited in the DDBJ Sequence Read Archive (DRA) with accession number DRA006403.
Bold show upregulated. Italic show downregulated.