Table 1.
Patient demographics.
| Demographic (N = 30) | Median (range) or N (%) |
|---|---|
| Age at recruitment (in days) | 84 (35–235) |
| Gender (female) | 17 (57%) |
| CFTR Genotype | |
| Homozygous p.Phe508Del | 12 (40%) |
| Heterozygous p.Phe508Del | 17 (57%) |
| Other | 1 (3%) |
| Extra-pulmonary features | |
| Pancreatic insufficiency | 22 (73%) |
| Meconium ileus | 1 (3%) |
| GORD | 8 (27%) |
| Birth history | |
| Mode of delivery | |
| Vaginal delivery | 21 (70%) |
| Caesarian section | 6 (20%) |
| Feeds in infancy | |
| Breastfeeding (exclusively or in combination with formula) | 16 (53%) |
| Exclusively formula fed | 14 (47%) |
| Exacerbations & antibiotic use | |
| Exacerbations | 7 (23%) |
| Prophylactic antibiotics at recruitment | 25 (83%) |
| Bacterial growth on TS culture | |
| P. aeruginosa | 7 (23%) |
| S. aureus | 1 (3%) |
| H. influenzae | 1 (3%) |
| Upper respiratory tract flora | 1 (3%) |
CFTR – cystic fibrosis transmembrane conductance regulator; GORD - gastro-oesophageal reflux disease; TS - throat swab. P. aeruginosa – Pseudomonas aeruginosa. S. aureus – Staphylococcus aureus. H. influenzae – Haemophilus influenzae.