Table 3.
List of OTUs showing significant (Padj < 0.05) changes in relative abundance with age.
| OTU name | r value | Adjusted P-value |
|---|---|---|
| Actinomyces (OTU ID 2665) | 0.25 | <0.001 |
| Alysiella (OTU ID 2166) | 0.23 | 0.006 |
| Atopobium (OTU ID 1256) | 0.21 | 0.013 |
| Capnocytophaga (OTU ID 812) | 0.20 | 0.016 |
| Enterococcus (OTU ID 1712) | 0.20 | 0.014 |
| Haemophilus (OTU ID 2347) | 0.23 | 0.006 |
| Haemophilus (OTU ID 2369) | 0.24 | 0.003 |
| Lachnoanaerobaculum (OTU ID 251) | 0.26 | <0.001 |
| Lactobacillus (OTU ID 1586) | 0.19 | 0.025 |
| Lautropia (OTU ID 2253) | 0.26 | <0.001 |
| Leptotrichia (OTU ID 1059) | 0.26 | <0.001 |
| Neisseria (OTU ID 2124) | 0.19 | 0.025 |
| Prevotella (OTU ID 657) | 0.26 | <0.001 |
| Prevotella (OTU ID 692) | 0.19 | 0.020 |
| Rothia (OTU ID 2603) | 0.21 | 0.013 |
| Streptococcus (OTU ID 412) | 0.23 | 0.006 |
| Streptococcus (OTU ID 432) | 0.25 | 0.002 |
| Streptococcus (OTU ID 1841) | 0.24 | 0.004 |
| Streptococcus (OTU ID 1897) | −0.19 | 0.016 |
| Veillonella (OTU ID 1463) | 0.24 | 0.006 |
Assessed using Spearman rank multiple correlation testing with FDR correction. Several species of Streptococcus spp., Haemophilus spp. and Prevotella spp., as well as other individual species showed a small (r < 0.3) but significant positive correlation with age in the first two years of life.