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. 2019 Mar 26;9:5132. doi: 10.1038/s41598-019-41546-x

Figure 3.

Figure 3

Overview of the anapyrexia induction procedures. (A) Schematic overview of the experimental setup used for animal temperature measurements in an airtight cage. A single box is depicted for simplicity of the otherwise 9 boxes arranged in a 3 × 3 array. A thermographic camera (CAM) was employed to record temperature. FiO2 was controlled by the gas mixture connected to the gas inlet of the cage, whereas O2 and CO2 concentrations were measured at the outlet. An adapted version of this drawing was published before under CC BY license (https://creativecommons.org/licenses/by/4.0) by our group18. (B) Representative FiO2 dynamics in mice during the atmosphere change from normoxia to hypoxia (-1–8.5 min) and back to normoxia (59–70 min).