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. 2019 Mar 26;9:5165. doi: 10.1038/s41598-019-41621-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Exogenous CCL21 administration macroscopically enhances cartilage repair in rabbits. (A) Macroscopic morphology of the osteochondral defect at 4 weeks postoperatively (n = 10/group). (B) Macroscopic morphology of the osteochondral defect at 16 weeks postoperatively (n = 10/group). (C) Macroscopic scores at 4 weeks postoperatively (n = 10/group). (D) Macroscopic scores at 16 weeks postoperatively (n = 10/group). Repair scoring range: 0–8. All values are expressed as mean ± SD. *P < 0.05, **P < 0.01, statistically significant (Steel-Dwass test).