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. 2019 Mar 26;9:5174. doi: 10.1038/s41598-019-41595-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Proposed survival decision tree grouping of MIBC patients into three distinct groups, which results in the proposed ‘TB stage model’. The leave one out cross-validated log rank test p value between the two resulting branches is indicated at each node. The first decision is based on the clinical parameter TNM stage and the second decision on the feature ‘number of TB in core’. The number of patients is indicated for each resulting group/leaf.