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. 2019 Mar 26;9:5184. doi: 10.1038/s41598-019-40163-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Mt transfer from BM-MSCs to STZ-PTECs in STZ mice. (a) Experimental protocol for the administration of BM-MSCs in STZ mice (n = 5 per group). (b) Immunofluorescence images of megalin (green) expression and localisation of MtDsRed2-MSC-derived Mt (red, white arrows) in proximal tubules of the kidney of STZ mice. Images were obtained 3 and 7 d after systemic administration of MtDsRed2-MSCs. Nuclei are counterstained with DAPI (blue). PT, proximal tubules. Scale bar, 10 µm.