Table 2.
Tumor and tumor samples properties.
| Samples’ properties: | mean | sd | min | max |
|---|---|---|---|---|
| tumor % | 66 | 33 | 0 | 99 |
| necrosis % | 5 | 11 | 0 | 63 |
| lymph node % | 12 | 23 | 0 | 97 |
| connective tissue % | 17 | 26 | 0 | 100 |
| Tumor properties | n | % | ||
| tumor cell size | <20 microns | 98 | 88 | |
| 20–25 microns | 2 | 2 | ||
| >25 microns | 1 | 1 | ||
| tumor cell shape | epithelioid | 82 | 74 | |
| mixed epithelioid and spindle | 17 | 15 | ||
| spindle | 2 | 2 | ||
| Tumor cell pigmentation | 0 | 48 | 43 | |
| 1 | 20 | 18 | ||
| 2 | 13 | 12 | ||
| 3 | 20 | 18 | ||
| Lymphocyte density | 0 | 17 | 15 | |
| 1 | 37 | 33 | ||
| 2 | 33 | 30 | ||
| 3 | 11 | 10 | ||
| Lymphocyte distribution | 0 | 17 | 15 | |
| 1 | 35 | 32 | ||
| 2 | 25 | 23 | ||
| 3 | 21 | 19 | ||
| Immunoscore, = sum of lymphocyte density and distribution | 0 | 15 | 14 | |
| 1 | 3 | 3 | ||
| 2 | 24 | 22 | ||
| 3 | 18 | 16 | ||
| 4 | 16 | 14 | ||
| 5 | 16 | 14 | ||
| 6 | 6 | 5 | ||
Tumor cell pigmentation (0 = absent: no melanin pigment discernible even at high power magnification, 1 = slight: melanin pigmentation hardly visible at low power, at high power, melanocytes show a faint diffuse hue or a few scattered melanin pigment granules, 2 = moderate: pigmentation visible at low power, the cytoplasm is translucent and appears significantly lighter than the hematoxylin stained nuclei, 3 = high: pigmentation is easily visible at low power, the cytoplasmic pigmentation reaches an intensity approximating that of the nucleus).
Lymphocyte distribution (0 = no lymphocytes within the tissue, 1 = lymphocytes present involving <25% of the tissue cross sectional area, 2 = lymphocytes present in 25 to 50% of the tissue, 3 = lymphocytes present in >50% of tissue).
Lymphocyte density (0 = absent, 1 = mild, 2 = moderate, 3 = severe).