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. 2019 Mar 26;9:5232. doi: 10.1038/s41598-019-41721-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of covariates age, gender and treadmill experience on acclimatization profiles during treadmill walking. Acclimatization of the twenty-six key walking parameters was characterized in three subgroup analyses. Stable parameters without any acclimatization are marked for each subgroup in blue (category 4, see methods), whereas walking parameters revealing acclimatization resulting in a stable plateau performance are illustrated in red (category 1). The duration of acclimatization (i.e. time to reach a stable plateau) is indicated for all subgroups in number of strides and seconds. Relative and absolute amplitudes of adaptations are provided to assess the extent of acclimatization. Reltative amplitudes (highest difference to first bin) of acclimatization are provided in percent. For the parameters with % as unit (DLS, swing phase), relative amplitudes represent the absolute difference to the first bin (i.e. absolute differences do not exist for these parameters). Abbreviations: Abs.: absolute; au: arbitrary units; ACC: angular component of coefficient of correspondence; COM: centre of mass; COV: coefficient of variation; DLS: double limb support; ROM: range of motion; Rel.: relative; SSD: sum of squared distances.