Table 1.
Correlation between NDRG1 and clinical factors.
| Patients | NDRG1 expression | p value | ||
|---|---|---|---|---|
| High (%) | Low (%) | |||
| Total | 100 | 35 (35.0) | 65 (65.0) | |
| Age (years) | 0.600 | |||
| <60 | 20 | 8 (40.0) | 12 (60.0) | |
| ≥60 | 80 | 27 (33.8) | 53 (66.2) | |
| Gender | 0.492 | |||
| Male | 76 | 28 (36.8) | 48 (63.2) | |
| Female | 24 | 7 (29.2) | 17 (70.8) | |
| Smoking | 0.059 | |||
| No | 50 | 22 (44.0) | 28 (56.0) | |
| Yes | 50 | 13 (26.0) | 37 (74.0) | |
| Multicentricity | 0.111 | |||
| No | 52 | 22 (42.3) | 30 (57.7) | |
| Yes | 48 | 13 (27.1) | 35 (72.9) | |
| Size (cm) | 0.142 | |||
| <3 cm | 50 | 14 (28.0) | 36 (72.0) | |
| ≥3 cm | 50 | 21 (42.0) | 29 (58.0) | |
| Lymph node metastasis | 0.034 | |||
| Negative | 94 | 30 (31.9) | 64 (68.1) | |
| Positive | 6 | 5 (83.3) | 1 (16.7) | |
| TNM Stage | 0.025 | |||
| NMIBC | 71 | 20 (28.2) | 51 (71.8) | |
| MIBC | 29 | 15 (51.7) | 14 (48.3) | |
| Pathological grade | 0.768 | |||
| G1 | 33 | 10 (30.3) | 23 (69.7) | |
| G2 | 44 | 16 (36.4) | 28 (63.6) | |
| G3 | 23 | 9 (39.1) | 14 (60.9) | |
NMIBC: non-muscle-invasive bladder cancer; MIBC: muscle-invasive bladder cancer.