Figure 4.

NMDA receptor-dependent component of granular layer excitation. A, VSDi normalized maps showing the spatial distribution of the NMDA component of excitation in WT and IB2 KO granular layers (average of 5 recordings in both cases). B, The plot shows the NMDA component as a function of distance from the center for the maps shown in A. Note that in the IB2 KO granular layer the NMDA component of excitation is larger and more extended compared with the WT granular layer. C, The histograms show, in WT and IB2 KO mice, the average values of the NMDA component normalized amplitude and of the core diameter. Data are reported as the mean ± SEM. **p < 0.01.