Table 3. Results of the multivariable analysis (Cox proportional hazard model) to examine the relationship between the risk of HIV acquisition and three PVL measures.
Geometric mean viral load* | Prevalence detectable viremia† |
Community transmission index‡ |
|||||||
---|---|---|---|---|---|---|---|---|---|
HR | (95% CI) | P | HR | (95% CI) | P | HR | (95% CI) | P | |
Population-based: HIV-positive cases only | |||||||||
Model A2: Adjusted HR without HIV prevalence | 1.000 | (1.000–1.000) | 0.817 | 1.005 | (0.994–1.015) | 0.401 | 1.037 | (0.990–1.086) | 0.130 |
Model A3: Adjusted HR with HIV prevalence | 1.000 | (1.000–1.000) | 0.475 | 1.008 | (0.996–1.019) | 0.190 | 1.048 | (0.999–1.100) | 0.057 |
Population-based: HIV-positive and HIV-negative cases | |||||||||
Model B2: Adjusted HR without HIV prevalence | 1.079 | (1.046–1.113) | <0.001 | 1.070 | (1.039–1.103) | <0.001 | 1.224 | (1.121–1.337) | <0.001 |
Model B3: Adjusted HR with HIV prevalence | 1.091 | (1.045–1.138) | <0.001 | 1.063 | (1.025–1.103) | 0.001 | 1.193 | (1.079–1.320) | 0.001 |
N | 8,732 | 8,732 | 8,732 |
For a one unit increase in geometric mean viral load.
For a 1% increase in the prevalence of detectable viremia.
For a predicted one transmission event increase per 100 sexual contacts.