Table 3. Risk factor for mortality in patients with lung cancer assessed by Cox proportional hazards model.
Parameter | HR | 95% CI | p-value |
---|---|---|---|
Univariate analysis | |||
Age | 1.048 | 1.035–1.061 | <0.001 |
Male sex | 1.751 | 1.345–2.280 | <0.001 |
Under weight patient (BMI<18.5) | 2.009 | 1.384–2.915 | <0.001 |
BMI, kg/m2 | 0.906 | 0.869–0.945 | <0.001 |
Ever smoker | 1.714 | 1.323–2.220 | <0.001 |
Asymptomatic patient | 0.265 | 0.160–0.439 | <0.001 |
Weight loss | 1.577 | 1.029–2.417 | 0.037 |
Performance status 2–4 | 3.135 | 2.206–4.456 | <0.001 |
Small cell lung cancer | 2.488 | 1.807–3.425 | <0.001 |
Distant metastasis | 4.142 | 3.179–5.397 | <0.001 |
Any treatment | 0.242 | 0.187–0.314 | <0.001 |
Multivariate analysis | |||
Age | 1.037 | 1.020–1.055 | <0.001 |
BMI, kg/m2 | 0.904 | 0.864–0.945 | <0.001 |
Ever smoker | 2.003 | 1.394–2.876 | <0.001 |
Asymptomatic patient | 0.387 | 0.195–0.765 | 0.006 |
Small cell lung cancer | 1.627 | 1.077–2.458 | 0.021 |
Distant metastasis | 3.990 | 2.812–5.661 | <0.001 |
Any treatment | 0.364 | 0.253–0.522 | <0.001 |
HR: hazard ratio; CI: confidence interval; BMI: body mass index.