Table 1.
Effect of magnesium taurate on CAT, GPx, GSH, SOD, and MDA level in heart.
| CAT (μmoles of H2O2 consumed/min/mg protein) |
GPx (μmoles GSH oxidised/min/mg protein) |
GSH (μmoles/g tissue) |
SOD (U/min/mg protein) |
MDA (μmoles/g tissue) |
|
|---|---|---|---|---|---|
| Normal | 33.40 ± 2.08 | 2.40 ± 0.07 | 6.95 ± 0.10 | 9.50 ± 0.54 | 5.30 ± 0.25 |
| Toxic control | 11.20 ± 1.06c | 0.94 ± 0.07c | 4.26 ± 0.05c | 3.82 ± 0.21c | 8.48 ± 0.29c |
| Standard | 26.40 ± 1.20bf | 2.10 ± 0.06bf | 6.67 ± 0.11af | 7.34 ± 0.19cf | 6.76 ± 0.26bf |
| MgT (2 mg/kg) | 24.00 ± 1.22cf | 1.59 ± 0.07cf | 5.32 ± 0.11cf | 6.34 ± 0.28cf | 6.74 ± 0.26bf |
| MgT (4 mg/kg) | 26.80 ± 1.28bf | 1.93 ± 0.05cf | 6.37 ± 0.04cf | 8.12 ± 0.28bf | 6.26 ± 0.30af |
Values are expressed as mean ± SEM; n = 6 in each; aP < 0.05;bP < 0.01;cP < 0.001 when compared to normal and dP < 0.05;eP < 0.01;fP < 0.001 when compare to toxic control (one-way ANOVA followed by Newman Keuls post hoc test). CAT: catalase; GPx: glutathione peroxidase; GSH: reduced glutathione; SOD: superoxide dismutase; MDA: malondialdehyde.