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. 2019 Mar 14;10:177. doi: 10.3389/fphys.2019.00177

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Copyright © 2019 Alves, de Queiroz, Bär and dos Santos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Performed simulations: (A) healthy, (B) ischemic, and (C) infarct. (D) Shows the regions of interest for the evaluation of CA signal intensity. When simulating ischemia and infarct, we sum up the concentration of CA in these regions of interest, for each time instant. The colored circle that surrounds the epicardium represents the pressure boundary condition for each scenario. Note the different minimum values of the two color bars.