Table 1.
Healthy controls N = 10 | Primary Raynaud phenomenon N = 10 | Systemic sclerosis N = 10 | |
---|---|---|---|
Age (years), mean ± SD | 29.9 ± 2.7 | 47.8 ± 16.2 | 56.2 ± 11.5 |
Female gender, n | 7 | 8 | 5 |
Weight (kg), mean ± SD | 71.3 ± 11.7 | 64.4 ± 11.9 | 73.3 ± 11.3 |
Height (cm), mean ± SD | 177 ± 8.7 | 170 ± 10.0 | 176 ± 5.9 |
Smoking, n | |||
Current | 0 | 1 | 2 |
Past smoker | 0 | 3 | 7 |
Comorbidities, n | |||
Hypertension | 0 | 1 | 2 |
Hypercholesterolemia | 0 | 0 | 1 |
Diabetes | 0 | 1 | 0 |
ACR/EULAR score ≥9, n | 0 | 0 | 10 |
Disease duration (years), median (IQR) | N/A | 8.0 (4.0‐17.0) | 4.5 (3.0‐6.3) |
Abnormal NCM pattern, n | 0 | 0 | 10 |
Positive autoantibodies, n | 0 | 0 | 8 |
Organ involvement, n | |||
Pulmonal | 0 | 0 | 0 |
Esophageal | 0 | 0 | 3 |
Creatinine, median (IQR) | 72.1 [66.5‐77.6] | 72.0 [63.5‐72.0] | 76.2 [63.5‐88.6] |
eGFR, median (IQR) | 94.5 [90.6‐114.8] | 79.3 [68.3‐97.4] | 86.6 [74.1‐98.5] |
Digital ulcers, n | 0 | 0 | 6 |
Medication, n | |||
Nifedipine | 0 | 1 | 2 |
Iloprost | 0 | 0 | 2 |
Bosentan | 0 | 0 | 3 |
ACR/EULAR, The American College of Rheumatology/European League Against Rheumatism (EULAR); NCM, Nailfold Capillary Microscopy.