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. 2019 Mar 20;10:160. doi: 10.3389/fendo.2019.00160

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Copyright © 2019 Dunk, Kwan, Hazan, Walker, Wright, Harris, Jones, Keating, Kingdom, Whittle, Maxwell and Lye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IUGR PBBx display high numbers of preserved uterine spiral arteries. Graphs show quantitation of the degree of remodeling of all myometrial vessels control (circle), IUGR (square) and IUGR with preeclampsia (triangle) groups. Preserved vessels were scored when intact multi layered vascular smooth muscle media was present (A). Disorganized vessels were scored when the vascular media was separated and smooth muscle cells were migrating away from the outer layers of the media (B). Destroyed vessels were scored when all media had been lost and replaced with fibrin (C). *p < 0.05, **p < 0.01.