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. 2019 Mar 19;13:242. doi: 10.3389/fnins.2019.00242

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Copyright © 2019 Dong, Wang, Yang, Shen, Qu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Striatal dLight1.1 fluorescent signal in response to a new environment. (A) Schematic showing the cage-change procedure, where mice were moved to a new cage. (B) A typical example of the fluorescence signal, EEG, and EMG traces before and after the cage-change. (C) Time course of the striatal dLight1.1 signal in response to the cage-change, (black is to home cage, green is to new cage). (D) Average striatal dLight1.1 signal 30 min before, 30 min and 30–120 after the cage change to home cage or new cage (one-way ANOVA, home cage: F_2,4 = 7.284, P = 0.0464; new cage: F_2,12 = 10.1832, P = 0.0026. post comparisons followed by PLSD).