Table 1.
Studies that met inclusion/exclusion criteria for systematic review
| References | Study design | Country | Study population | Diagnosis assessment | Results | Quality* |
|---|---|---|---|---|---|---|
| Chen et al. 1995[18] | Cross-sectional study | USA | Pt. with BD, unipolar disorder or any Axis I disorder other than bipolar or unipolar disorder (n=6622, age >18): BD (n=167) | DIS; DSM-III | Higher lifetime rates of “thoughts of suicide”, “suicide attempts”, “thoughts of death” and “wanting to die” in BD-OCD pt. vs BD pt. | 25/31 |
| Dilsaver et al. 2006[19] | Case-control study | USA | Latino adolescents (n=313): BD (n=115, mean age=14.6±1.5) | SCID; DSM-IV | BD-OCD pt. associated with a 2.4 fold increase in the odds of suicidal ideation vs BD pt. (95% CI=1.0-5.8). | 18/31 |
| Goes et al. 2012[13] | Cross-sectional study | USA | BD (n=1416, mean age=42.0), first-degree relatives with BD (n=850) | DIGS; DSM-IV | Higher rates of history of suicide attempts in BD-OCD pt. vs BD pt. (48.3 vs. 29.6%). | 23/31 |
| Jeon et al. 2018[20] | Case-control study | Korea | BD (n=264, mean age=35.5), BD-OCD (n=50, mean age=31.8) | SCID; DSM-IV | No statistically significant differences between BD-OCD patients and BD patients in terms of a history of suicidal attempts. | 23/31 |
| Kazhungil et al. 2017[14] | Case-control study | India | BD-I (n=90, mean age=21.69) | SCID; DSM-IV | Higher rates of suicide attempts in BD-OCD pt. vs BD pt. (0.29±0.59 vs. 1.19±0.93). | 23/31 |
| Koyuncu et al. 2010[21] | Case-control study | Turkey | BD (n=214, mean age: BD=34.8±10.3, BD-OCD=36.2±15.9) | SCID; DSM-IV | No statistically significant differences between BD-OCD pt. and BD pt. in terms of lifetime suicide attempts. | 20/31 |
| Kruger et al. 2000[15] | Case-control study | Germany | BD-I or BD-II (n=143, mean age=44) | SCID; DSM-III-R | Higher incidence of prior suicide attempts in BD-OCD pt. vs BD pt. (90% vs. 38%). | 22/31 |
| Magalhaes et al. 2010[16] | Case-control study | Brazil | BD (n=259, mean age=41) | SCID; DSM-IV | Higher rates of history of suicide attempts in BD-OCD pt. vs BD pt. (70% vs. 35%). | 23/31 |
| Shashidhara et al. 2015[22] | Case-control study | India | BD-I (n=396, mean age=22.55) | MINI-BIPOLAR; DSM-IV | No statistically significant differences between BD-OCD pt. and BD pt. in terms of current suicide risk. | 23/31 |
| Simon et al. 2004[17] | Cross-sectional study | USA | BD (n=475, mean age=41.7±12.8) | MINI; DSM-IV | Higher rates of history of suicide attempts in BD-OCD pt. vs BD pt. | 23/31 |
BD: bipolar disorder; OCD: obsessive-compulsive disorder; DSM: Diagnostic and Statistical Manual of Mental Disorders; SCID: Structured Clinical Interview; DIS: Diagnostic Interview Schedule; DIGS: Diagnostic Instrument for Genetic Studies; MINI: Mini International Neuropsychiatric Interview; MINI-BIPOLAR: MINI: Mini International Neuropsychiatric Interview for Bipolar Disorders Studies. *Checklist for measuring study quality developed by Downs and Black