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. 2019 Mar 20;10:555. doi: 10.3389/fmicb.2019.00555

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Copyright © 2019 Araújo, Pereira, Portis, dos Santos Junior, Fontes, de Sousa, Assunção, Baeza, Bailão, Ricart, Brock and Soares.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram of the metabolic processes differentially expressed in yeast cells and heatmap of proteins in mycelium, mycelium-to-yeast transition, and yeast cells. (A) The figure summarizes the data obtained from proteomic analysis; enzymes are listed as follows: Acad, acyl-CoA dehydrogenase; ECH, enoyl-CoA hydratase; ACAT, ketoacyl-CoA thiolase; MCS, methylcitrate synthase; MCD, methylcitrate dehydrogenase; ACO, aconitase; CS, citrate synthase; SUCLA, succinyl-CoA ligase; PDH, pyruvate dehydrogenase; ATPase, ATP synthase; ANT, aspartate aminotransferase; HPPD, hydroxyphenylpyruvate dioxygenase; FAH, fumarylacetoacetase; CRAT, carnitine acetyltransferase; SRM, spermidine synthase; MTAP, methylthioadenosine phosphorylase; MTCBP, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase. (B) The color scale shows the mean of abundance of differentially expressed proteins (p-value ≤ 0.05). Functional categories were obtained by manual search in the annotation database Pedant (http://pedant.gsf.de/) on MIPS that provides a tool to search the Functional Categories (Funcat 2.0). Red represents significantly higher expression and green represents a significantly low level of expression.