Table 5. Summary of Reported IrAEs Involving Renal System: AKI.

References	Presentation	Number of cases	Age (mean)	Immune checkpoint inhibitors (number of cases)	Doses (mean)	Labs		Treatments (outcome)
						Urine studies	Biopsy
[106-113]	AKI	16	43 - 78 (67)	Pembrolizumab-5, nivolumab-6, ipilimumab-1, nivolumab/ipilimumab-3, pembrolizumab/nivolumab-1	2 - 5 (3)	Proteinuria-6, hematuria-3, WBC casts-3, granular casts-2, eosinophils-2, normal-1, N/A-2	Interstitial nephritis-10, tubular-interstitial injury-3, IgA nephropathy-1, minimal change disease-1, acute post-infectious glomerulonephritis-1	Steroids, improved AKI-15, hemodialysis-1
[111]	Nephrotic syndrome	1	45	Ipilimumab	4	Proteinuria	Minimal change disease	Corticosteroids, proteinuria improved

AKI: acute kidney injury.