Figure 2.

Effects of compound 11 on ASIC3 channels. (A) Chemical structures of natural compounds with phenol groups including (‐)‐epigallocatechin gallate (EGCG, compound 11). (B) Compound 11 dosedependently inhibits pH5.0‐evoked inward currents in ASIC3‐transfected CHO cells. (C) Concentrationresponse relationship of compound 11 on ASIC3 currents. Each point is the mean ± S.E.M. of 6 measurements normalized to the pH 5.0‐induced peak currents, and the solid line was the fit to the Hill equation