Figure 6.

Brain glucose metabolism was measured with [¹⁸F]FDG positron emission tomography (PET) imaging to investigate whether stroke induction can lead to detectable changes in glucose metabolism (SC vs CC) and whether dietary intervention has an impact on glucose metabolism following stroke induction (SC vs SI‐post and SC vs SI‐pre). Differences in brain metabolism caused by ischemia and by the investigational diet in animals sacrificed on day 7. (A) [¹⁸F]FDG standardized uptake values (SUV) uptake in the whole brain (A, B) and somatosensory cortex ipsilateral to the lesion (C, D) on day 7 and day 21 following ischemia. CC ₇, CC ₂₁ = control group (n = 6, n = 4), SC ₇, SC ₂₁ = stroke + control diet (n = 6, n = 5), SI‐post₇, SI‐pre₇, SI‐pre₂₁ = stroke + preischemic dietary intervention (n = 6, n = 6), SI‐post₂₁ = stroke + postischemic dietary intervention (n = 6, n = 5)