Figure 2. Zwitterionic polymer coating of Medtronic CGMs.
(a) Synthesis scheme for the identified hit polymer, poly(MPC). (b) Illustration of the modification of the sensor electrode surface with zwitterionic poly(MPC) through dopamine-mediated conjugation. (c) and (d) examination of the electrode surface coating using XPS analysis. The characteristic peaks of phosphorus groups of the poly(MPC) at 188 eV (P2p peak) and at 131 eV (P2s peak) were examined. (e) The control and coated sensors were examined using an in vitro glucose sensing assay. Experiments repeated at least 3 times.
