. Author manuscript; available in PMC: 2019 Mar 27.

Published in final edited form as: Acta Oncol. 2009;48(7):955–963. doi: 10.1080/02841860903104145

Table III.

Case-control studies on polymorphisms of GABA receptors and serotonin transporters and focal epilepsy.

First Author	Gene, specific poly-morphisms	Epilepsy type	Number of patients and controls	P-value, odds ratio and confidence interval
Gambardella [39]	GABA (B) receptor G1465A	Non-lesional TLE	141 cases and 372 controls	OR=6.47; CI=2.02–20.75 p=0.003
Ma [40]	G1465A	TLE preceded by febrile seizures (FS)	120 cases, 218 controls	NS
Ma [41]	GABRA1, GABRA5, GABRG2, GABRD	Familial focal epilepsy preceded by FS	74 cases, 118 controls	NS
Manna [42]	Serotonin transporter (5-HTT)	TLE	276 cases, 309 controls	5-HTTLPR: p=0.0086;
Manna [42]	5-HTTLPR 5-HTTVNTR			5-HTTVNTR: NS