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. 2019 Mar 27;15(3):e1008075. doi: 10.1371/journal.pgen.1008075

Fig 5. Human chromosome 15 evolution and GOLGA core elements dispersion.

Fig 5

A fission event of an ancestral chromosome led to human and great ape chromosomes 14 (green ideogram) and 15 (blue ideogram). The zoomed-in view shows how the inactivation of the ancestral centromere after the fission event released the recombination constraints typical of pericentromeric regions leading to two inversions, shown with the white arrows, which resulted in a dispersal of GOLGA repeats (purple blocks) and segmental duplications (gray bars). AC, ancestral centromere. NC, neocentromere.