Table 4.
Pathway/GO terms |
q-value* |
|
---|---|---|
amyloid-β | tangles | |
Regulation of neuron projection development | 3.88×10−12 | 3.43×10−12 |
Calcium ion transmembrane transporter activity | 2.10×10−9 | 2.42×10−5 |
Postsynapse | 6.94×10−9 | 8.00×10−11 |
Calcium ion transmembrane transport | 1.04×10−8 | 1.16×10−4 |
Positive regulation of cell projection organization | 1.73×10−8 | 4.03×10−7 |
Positive regulation of neuron projection development | 2.48×10−8 | 4.07×10−8 |
Cell leading edge | 2.94×10−8 | 4.22×10−8 |
Positive regulation of neuron differentiation | 8.55×10−8 | 6.84×10−8 |
Divalent inorganic cation transmembrane transporter activity | 2.71×10−7 | 1.69×10−3 |
Calcium ion transport | 1.29×10−6 | 8.72×10−5 |
Actin binding | 1.51×10−6 | 4.07×10−8 |
REACTOME: Axon guidance | 2.15×10−6 | 1.19×10−5 |
Positive regulation of nervous system development | 3.77×10−6 | 4.36×10−7 |
Cell projection membrane | 5.90×10−6 | 2.04×10−6 |
Divalent inorganic cation transport | 5.90×10−6 | 6.08×10−4 |
Regulation of dendrite development | 8.98×10−6 | 1.60×10−4 |
Gtpase binding | 9.91×10−6 | 6.31×10−5 |
Synaptic membrane | 1.02×10−5 | 4.07×10−8 |
Guanyl nucleotide exchange factor activity | 1.21×10−5 | 6.84×10−8 |
Main axon | 1.55×10−5 | 8.56×10−4 |
Excitatory synapse | 2.39×10−5 | 2.93×10−9 |
Regulation of small gtpase mediated signal transduction | 2.39×10−5 | 1.08×10−6 |
Regulation of cell morphogenesis involved in differentiation | 8.82×10−5 | 4.36×10−7 |
Cation channel activity | 1.17×10−4 | 1.31×10−6 |
Neuron porjection morphonenesis | 1.31×10−4 | 4.03×10−7 |
Axon | 1.33×10−4 | 9.97×10−8 |
Receptor complex | 2.27×10−4 | 1.50×10−6 |
Ras guanyl nucleotide exchange factor activity | 1.42×10−3 | 4.36×10−7 |
Gated channel activity | 3.47×10−3 | 1.06×10−7 |
Neuronal postsynaptic density | 3.99×10−2 | 1.11×10−6 |
Adjusted for multiple testing by the Benjamini-Hochberg method