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. 2019 Mar 27;5(3):eaav9020. doi: 10.1126/sciadv.aav9020

Table 3. Multivariate analysis of maternal reports of infection and physician-notified AEs as a predictor of plasma hepcidin.

No. of events Geometric mean hepcidin
(% >5.5 ng/ml)
F ratio P*
Illness
Yes
Illness
No
Maternal reports
  Any sickness 341 5.43 (45%) 4.33 (45%) 8 0.0052
Clinical records
  AEs 425 6.19 (59%) 4.23 (44%) 31 <0.0001
  Fever 154 7.50 (68%) 4.30 (44%) 26 <0.0001
  Diarrhea 129 4.95 (49%) 4.37 (45%) 1 NS
  Respiratory 154 6.92 (64%) 4.31 (44%) 19 <0.0001
  Skin 114 5.41 (54%) 4.36 (45%) 3 0.09

*P values obtained from multilevel linear modeling included subject, treatment group, and time as covariates.

†Number of reported illnesses at twice weekly fieldworker visits coinciding with hepcidin measurements (total n = 5113).

‡Number of recorded AEs coinciding with hepcidin measurements ±4 days (total n = 5113).