Table 1.
Demographics and disease characteristics
| Weak (n=7) | Typical (n=30) | Weak-Visuospatial/Strong-Memory (n=9) | Weak-Visuospatial (n=21) | Amnestic (n=26) | Strong (n=29) | Statistical comparison | |
|---|---|---|---|---|---|---|---|
| Age | 66.29 (7.65) | 65.43 (4.78) | 59.89 (9.2) | 63.43 (8.15) | 64.81 (6.74) | 61.14 (7.12) | F(5, 116)=2.039, p=.078 |
| Gender, male (%) | 100 | 76.7 | 44.4 | 66.7 | 80.8 | 69 | χ2(5)=7.971, p=.158 |
| Years of education | 13 (3.32) | 14.7 (2.22) | 15 (1.87) | 15.24 (2.59) | 14.73 (2.95) | 15.9 (2.5) | F(5,110)=1.506, p=.194 |
| Handedness, right (%) | 71.4 | 93.3 | 77.8 | 85.7 | 88.5 | 86.2 | χ2(5)=13.229, p=.211 |
| Family history of PD (%) | 28.6 | 16.7 | 11.1 | 19 | 30.8 | 17.2 | χ2(5)=2.937, p=.710 |
| APOEe4 carrier (%) | 28.6 | 26.7 | 44.4 | 28.6 | 26.9 | 6.9 | χ2(5)=10.420, p=.404 |
| Disease duration, months | 7.17 (8.28) | 4.86 (4.74) | 5.25 (6.23) | 7.81 (6.96) | 9.27 (8.19) | 5.42 (7.42) | F(5,110)=1.487, p=.200 |
| Dominantly affected side, right (%) | 14.3 | 33.3 | 22.2 | 52.4 | 38.5 | 41.4 | χ2(5)=11.177, p=.344 |
| HYS, 1 (%) | 33.3 | 44.8 | 37.5 | 28.6 | 23.1 | 61.5 | χ2(5)=9.707, p=.084 |
| MDS-UPDRS total score | 39.83 (16.87) | 30.72 (13.76) | 29.88 (11) | 35.38 (14.51) | 34.08 (12.1) | 28.35 (11.86) | F(5, 110)=1.330, p=.257 |
| MDS-UPDRS Part I | 2.67 (2.16) | 0.93 (1.07) | 1.88 (1.81) | 1.05 (1.2) | 1.58 (1.98) | 0.77 (0.99) | F(5,100)=2.643, p=.027* |
| MDS-UPDRS Part I Patient Questionnaire | 5 (4.24) | 4 (3.93) | 3.88 (3.09) | 3.95 (2.82) | 5.08 (3.15) | 4.5 (2.92) | F(5,110)=.462, p=.804 |
| MDS-UPDRS Part II | 6.33 (3.56) | 4.69 (3.89) | 5.5 (4) | 5.91 (4.17) | 5.65 (4.05) | 5.65 (3.42) | F(5,110)=.462, p=.867 |
| MDS-UPDRS Part III | 25.83 (10.94) | 21.1 (9.32) | 18.63 (5.76) | 24.48 (8.89) | 21.77 (8.8) | 17.42 (7.85) | F(5,110)=2.079, p=.073 |
| MoCA | 26.29 (2.5) | 27.47 (1.96) | 28.44 (1.59) | 26.48 (2.54) | 26 (2.62) | 27.59 (2.04) | F(5,116)=2.788, p=.020* |
PD: Parkinson’s Disease Rating Scale; MoCA: Montreal Cognitive Assessment.
All variables are stated as mean (standard deviation) or percentage where applicable.
Statistical significance is marked with *.