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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Vet Cardiol. 2018 Dec 14;22:2–19. doi: 10.1016/j.jvc.2018.10.004

Figure 3: Pacing induced automaticity depression and sinoatrial node (SAN) exit blocks during adenosine (Ado) perfusion in failing canine and human hearts.

Figure 3:

(A) Sinoatrial node optical action potential (OAP) and atrial electrocardiogram (ECG) recordings during and after pacing showing 2:1 SAN entrance block and subsequent exit blocks in a canine heart failure (HF) model. (B) Atrial and SAN OAPs during and after pacing showing exit blocks. [Data modified from (A) Lou et al. Circulation 2014 [19] and (B) Li et al. Sci Transl Med 2017 [11]]. SACT: sinoatrial conduction time; (c)SNRTi/d: (corrected) sinus node recovery time, indirect/direct.