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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Biochim Biophys Acta Biomembr. 2019 Mar 13;1861(5):1030–1036. doi: 10.1016/j.bbamem.2019.03.005

Figure 1: Model structure of CL ND.

Figure 1:

A) In this depiction, CL (polar head groups in pink) is organized as a disk-shaped bilayer whose perimeter is circumscribed and stabilized by apoA-I (green/blue helices), which interacts with CL fatty acyl chains at the edge of the disk. B) FPLC size exclusion chromatography profile of CL ND. ND were formulated with apoA-I and CL as described. An aliquot of CL ND (0.32 mg apoA-I / 0.8 mg CL) in 20 mM HEPES buffer, pH 7.2, was applied to a Superose 6 Increase 10/300 GL column and elution monitored at 280 nm.