FIGURE 7.

Differential expression of genes with roles in RNA metabolism in GEMM cells, CMV⁺ cells, and the rest of the population. Heatmap (A,E,F) and distributions (B–D) of Log₂ ratio values obtained by dividing the mean number of transcripts/cell of genes with roles in RNA transcription, processing and translation as found in the CMV⁺ or GEMM clusters by the mean number of transcripts/cell in the rest of the cells (CMV/REST, green line, and GEMM/REST, blue line) or in GEMM cells (CMV/GEMM, red line). The heatmap color scales refer to the Log₂ ratio values. Numbers in white font in (E,F) report the Log₂ ratio values of each gene. The Wilcoxon signed rank test was used to identify populations with median values significantly different from zero. The population with the lowest P-value is highlighted by coloring of the area under the curve. The dashed line marks the ratio = 1 point. N, number of genes in each category.