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. 2019 Mar 21;10:174. doi: 10.3389/fendo.2019.00174

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Copyright © 2019 Tu, Cheung, Chan and Chan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The interaction between miRNAs and apoptosis pathway in GC. These miRNA-mRNA communications could greatly modulate GC apoptosis during the process of follicle atresia. MAP3K1, Mitogen-activated protein kinase 1; Klf4, Kruppel-like factor 4; SMAD2, SMAD family member 2; SMAD5, SMAD family member 5; SIRT1, NAD-dependent deacetylase sirtuin-1; IGF1, insulin like growth factor 1. Arrowhead line, promotion; Flat-end line, repression.