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. 2019 Mar 21;10:185. doi: 10.3389/fimmu.2019.00185

Table 1.

Frequencies of CNVs (CNRs, proportion of individuals with that number of copies is shown) and SNPs (allele frequencies are shown).

Variant European (n = 919) Chinese (n = 428) African (n = 508) Fisher's exact
CNR1
FCGR3B + FCGR2C 0 copies 0.00 0.00 0.00
1 copy 0.07 0.09 0.11
2 copies 0.83 0.73 0.73
3 copies 0.09 0.17 0.14
4 copies 0.01 0.01 0.01 <0.0001
CNR2
FCGR3A + FCGR2C 1 copy 0.01 0.01 0.01
2 copies 0.94 0.96 0.96
3 copies 0.04 0.04 0.03
4 copies 0.00 0.00 0.00 0.87
CNR3
FCGR3A + FCGR2C 1 copy 0.00* 0.00 0.00*
2 copies 1.00 0.98 1.00
3 copies 0.00 0.02 0.00 <0.001
FCGR2A
131 H 0.54 0.67 0.44
131 R 0.46 0.33 0.56 <0.0001
27 Q 0.88 1.00 0.89
27 W 0.12 0.00 0.11 <0.0001
FCGR3A
158 F 0.64 0.64 0.64
158 V 0.36 0.36 0.36 0.94
FCGR2C
Stop 0.84 1.00 0.90
Classic ORF 0.11 0.00 0.02
Nonclassic ORF 0.05 0.00 0.08 <0.0001
Promoter haplotype 2B.1 0.89 1.00 0.95
2B.2 0.11 0.00 0.05 <0.0001
FCGR3B
NA1 0.35 0.62 0.38
NA2 0.62 0.38 0.46
SH 0.02 0.00 0.15 <0.0001
FCGR2B
232I 0.88 0.74 0.73
232T 0.12 0.26 0.27 <0.0001
Promoter haplotype 2B.1 0.90 1.00 0.99
2B.4 0.10 0.00 0.01 <0.0001

Fisher's exact test: Overall P for differences between populations for that variation is shown. P-values < 0.05 are shown in bold.

*

1 European and 1 West African individual showed a deletion of CNR3.