Table 1.
Variant | European (n = 919) | Chinese (n = 428) | African (n = 508) | Fisher's exact | |
---|---|---|---|---|---|
CNR1 | |||||
FCGR3B + FCGR2C | 0 copies | 0.00 | 0.00 | 0.00 | |
1 copy | 0.07 | 0.09 | 0.11 | ||
2 copies | 0.83 | 0.73 | 0.73 | ||
3 copies | 0.09 | 0.17 | 0.14 | ||
4 copies | 0.01 | 0.01 | 0.01 | <0.0001 | |
CNR2 | |||||
FCGR3A + FCGR2C | 1 copy | 0.01 | 0.01 | 0.01 | |
2 copies | 0.94 | 0.96 | 0.96 | ||
3 copies | 0.04 | 0.04 | 0.03 | ||
4 copies | 0.00 | 0.00 | 0.00 | 0.87 | |
CNR3 | |||||
FCGR3A + FCGR2C | 1 copy | 0.00* | 0.00 | 0.00* | |
2 copies | 1.00 | 0.98 | 1.00 | ||
3 copies | 0.00 | 0.02 | 0.00 | <0.001 | |
FCGR2A | |||||
131 H | 0.54 | 0.67 | 0.44 | ||
131 R | 0.46 | 0.33 | 0.56 | <0.0001 | |
27 Q | 0.88 | 1.00 | 0.89 | ||
27 W | 0.12 | 0.00 | 0.11 | <0.0001 | |
FCGR3A | |||||
158 F | 0.64 | 0.64 | 0.64 | ||
158 V | 0.36 | 0.36 | 0.36 | 0.94 | |
FCGR2C | |||||
Stop | 0.84 | 1.00 | 0.90 | ||
Classic ORF | 0.11 | 0.00 | 0.02 | ||
Nonclassic ORF | 0.05 | 0.00 | 0.08 | <0.0001 | |
Promoter haplotype | 2B.1 | 0.89 | 1.00 | 0.95 | |
2B.2 | 0.11 | 0.00 | 0.05 | <0.0001 | |
FCGR3B | |||||
NA1 | 0.35 | 0.62 | 0.38 | ||
NA2 | 0.62 | 0.38 | 0.46 | ||
SH | 0.02 | 0.00 | 0.15 | <0.0001 | |
FCGR2B | |||||
232I | 0.88 | 0.74 | 0.73 | ||
232T | 0.12 | 0.26 | 0.27 | <0.0001 | |
Promoter haplotype | 2B.1 | 0.90 | 1.00 | 0.99 | |
2B.4 | 0.10 | 0.00 | 0.01 | <0.0001 |
Fisher's exact test: Overall P for differences between populations for that variation is shown. P-values < 0.05 are shown in bold.
1 European and 1 West African individual showed a deletion of CNR3.