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. 2019 Mar 7;32(2):293–306. doi: 10.1007/s10534-019-00185-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 6 — Top: Regional brain distribution of ⁶⁴Cu in 6-week-old (left panels) and 9-week-old (right panels) Npc1^−/− mice and age-matched controls at 30 min (top panels) and 15 h (bottom panels) post-injection of ⁶⁴Cu-GTSM. Data are mean [n = 6-7 Npc1^−/−, n = 5 WT)] ± SD. Statistically significant differences from healthy controls were evident in the 9-week-old groups and are indicated by * (p < 0.05) and ** (p < 0.01)