Table 2.

Reductions from baseline to 24 months in key measures before and after matching

	Prematching					Postmatching
Parameter	Mean	SD	N	p value	Effect size	Mean	SD	N b	p value	Effect size
HbA1c (%)
Continuers	– 0.78	1.47	2695	< 0.001	– 0.31	– 0.80	1.45	882	< 0.001	– 0.33
Discontinuers	– 0.31	1.50	885	< 0.001	– 0.31	– 0.32	1.50	882	< 0.001	– 0.33
Weight (kg)
Continuers	– 3.53	6.60	2600	< 0.001	– 0.34	– 3.57	6.46	839	< 0.001	– 0.34
Discontinuers	– 1.25	7.36	853	< 0.001	– 0.34	– 1.25	7.36	853	< 0.001	– 0.34
BMI (kg/m2)
Continuers	– 1.28	2.34	2599	< 0.001	– 0.34	– 1.29	2.28	838	< 0.001	– 0.34
Discontinuers	– 0.45	2.72	853	< 0.001	– 0.34	– 0.45	2.72	853	< 0.001	– 0.34
LDL (mg/dL)
Continuers	– 6.74	85.75	2623	0.231	– 0.05	– 5.72	84.06	867	0.472	– 0.03
Discontinuers	– 2.81	82.16	855	0.231	– 0.05	– 2.83	82.27	852	0.472	– 0.03
Triglyceridesa (mg/dL)
Continuers	– 13.90	127.49	2633	0.257	– 0.04	– 10.37	131.09	869	0.790	– 0.01
Discontinuers	– 6.81	152.23	860	0.257	– 0.04	– 6.89	152.49	857	0.790	– 0.01

BMI body mass index, HbA_1c glycated hemoglobin, LDL low-density lipoprotein, SD standard deviation

Effect size: 0.01 = very small, 0.2 = small, 0.5 = medium, 0.8 = large, 1.2 = very large, and 2 = huge.

^aStatistical test was calculated on a log scale

^bVariation in N between groups due to missing values