FIG 1.

Male and female WT and HVEM KO mice exhibit similar HSV-1 eye swab results and tissue titers after corneal inoculation. Eye swabs were collected at 1, 3, and 5 dpi, and periocular skin (POS), trigeminal ganglia (TG), and brain tissues were collected at 5 dpi. (A) Titers from eye swabs of male and female WT mice (n = 5 to 10 mice per group, 3 replicates). (B) Titers from tissues of male and female WT mice at 5 dpi (n = 4 to 5 mice per group, 3 replicates). (C and D) Titers from eye swabs of male and female HVEM KO mice (n = 5 to 10 mice per group, 3 replicates) (C) and from tissues of male and female HVEM KO mice (n = 3 to 5 mice per group, 2 replicates) (D). No difference was observed between the two sexes in each genotype. Titers calculated as means ± standard errors of the means (SEM) were analyzed using two-tailed t tests with Holm-Sidak's correction for multiple comparisons.