Fig. 2.

Nanohydroxyapatite deposition in ABCC6-Deficient Mice is Degraded Over 28 DPI. Beginning at 7DPI, Abcc6^+/+, Abcc6^+/−, or Abcc6^−/− animals were a assessed weekly by radiographic analysis through 28 DPI and quantified by the STiCCS, to reveal progressive resolution of nanohydroxyapatite from damaged skeletal muscle. b 3D µCT and histologic analysis at 28 DPI demonstrates reduced nanohydroxyapatite deposition compared to results seen in 7 DPI. H/E staining was utilized to assess sarcomere morphology and regeneration quantified in Table 2, and Von Kossa Staining was used to visualize calcification. Scale bar represents 100 µm. n ≥ 3 mice per genotype