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. 2019 Mar 21;10:412. doi: 10.3389/fimmu.2019.00412

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Copyright © 2019 Endres, Süß, Maier, Friedel, Nickel, Ziegler, Fiebich, Glocker, Stock, Egger, Lange, Dacko, Venhoff, Erny, Doostkam, Komlosi, Domschke and Tebartz van Elst.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-voxel magnetic resonance spectroscopy imaging. Presented is a MEGA-sLASER difference spectrum from the orbitofrontal cortex (OFC) of the patient, with indicated lactate (Lac)+ resonance. In the OFC, a Lac+/Creatine concentration ratio of 0.182 was found compared to a control group (N=6; 5 males and 1 female; 28 ± 2 years) with 0.159 ± 0.01.