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The resulting protein complex with the changed protein (A) Structure of the human respiratory chain complex I. The protein subunit carrying the mutation is highlighted in blue. (B) Schematic drawing of the complex I subunit altered in the patient. The site of the mutation in an extramembranous domain is indicated by an arrow. Data are derived from https://www.ebi.ac.uk/pdbe/entry/pdb/5xtc/protein/25 (20).
