Table 2.
Outcome data comparing patients with large-vessel occlusion according to time from symptom onset to reperfusion.
| Symptom onset to reperfusion 0–180 min (n = 192) |
Symptom onset to reperfusion 180–360 min (n = 876) |
Symptom onset to reperfusion >360 min (n = 393) |
p | All patients with available TTR (n = 1461) | |
|---|---|---|---|---|---|
| Outcome | |||||
| mRS 0–1 at 3 months | 67 (39.2%) | 224 (28.4%) | 88 (24.9%) | 0.003 | 379 (28.8%) |
| mRS 0–2 at 3 months | 94 (55.0%) | 369 (46.8%) | 135 (38.1%) | 0.001 | 598 (45.5%) |
| mRS 0–3 at 3 months | 117 (68.4%) | 484 (61.3%) | 189 (53.4%) | 0.002 | 790 (60.1%) |
| Mortality at 3 months | 33 (19.3%) | 176 (22.3%) | 84 (23.7%) | 0.520 | 293 (22.3%) |
| NIHSS at 24 h | 5 (IQR 2–13) | 8 (IQR 3–15) | 10 (IQR 4–17) | <0.001 | 8 (IQR 3–15) |
| Delta NIHSS admission – 24 h | 9 (IQR 5–15) | 6 (IQR 1–11) | 3 (IQR 0–7) | <0.001 | 5 (IQR 1–11) |
| Non-haemorrhagic worsening | 7 (4.2%) | 54 (8.0%) | 27 (9.4%) | 0.138 | 88 (7.8%) |
TTR: time from symptom onset to reperfusion; Delta NIHSS, difference in NIHSS between NIHSS at admission compared to 24 h; mRS, modified Rankin Scale; NIHSS, National Institute of Health Stroke Scale.