Table 3.

Analysis was done using time to reperfusion information in minutes, but association of TTR per hour increase with outcome data comparing patients with large-vessel occlusion in the anterior circulation is reported. Analysis was done using multivariable binary or ordinal logistic regression analysis adjusting for prespecified confounders outlined in the methods section for TTR per hour increase except aOR for successful reperfusion, which was analysed without successful reperfusion as variable.

Outcome	Unadjusted odds ratio (95% CI)	Adjusted odds ratio (95% CI)
mRS 0–1 at 3 months	0.928 (0.886–0.971)	0.929 (0.877–0.985)
mRS 0–2 at 3 months	0.928 (0.892–0.965)	0.933 (0.887–0.981)
mRS 0–3 at 3 months	0.951 (0.918–0.986)	0.955 (0.911–1.000)
Reperfusion at intervention (mTICI ⩾2B)	0.945 (0.906–0.985)	0.934 (0.885–0.984)
mRS at 3 months (shift)	1.046 (1.014–1.078)	1.038 (1.001–1.077)
Non-haemorrhagic worsening at 24 h	1.053 (0.998–1.110)	1.068 (0.996–1.144)
Mortality at 3 months	1.018 (0.979–1.058)	0.988 (0.933 – 1.046)
Symptomatic intracranial haemorrhage ECASS II definition	1.008 (0.944–1.076)	1.020 (0.927–1.123)

ECASS II, European Co-operative Acute Stroke Study-II; mRS, modified Rankin Scale; mTICI, modified treatment in cerebral ischaemia.