. 2019 Mar 27;10:2042018819834869. doi: 10.1177/2042018819834869

Table 2.

Summary of magnetic resonance spectroscopy studies evaluating myocardial triglyceride content in T2D.

Study	Patients	n	Mean age (years)	M/F	Mean BMI (kg/m²)	Key outcomes
McGavock ⁹⁶	Lean controls	15	35 ± 3	7/8	23 ± 2	Myocardial TG elevated in IGT and T2D versus controls (0.95 ± 0.60 versus 1.06 ± 0.62 versus 0.46 ± 0.30 fat/water, p < 0.05)
	Obese	21	36 ± 12	10/11	32 ± 5
	IGT	20	49 ± 9	5/15	31 ± 6
	T2D	78	47 ± 10	37/41	34 ± 7
Rijzewijk et al. ⁷²	Controls	28	54 ± 1	28/0	26.9 ± 0.5	Myocardial TG increased in T2D versus controls (0.96 ± 0.07% versus 0.65 ± 0.05%, p < 0.05)
Rijzewijk et al. ⁷²	T2D	38	57 ± 1	38/0	28.1 ± 0.6
Korosoglou et al. ⁷⁴	Controls	16	62 ± 3	10/6	23.9 ± 2.5	Myocardial TG in T2D 0.86 ± 0.14 Association between TG and mean diastolic strain rate (r = −0.71, p < 0.001) and peak systolic strain rate (r = 0.41, p = 0.02)
Korosoglou et al. ⁷⁴	T2D	42	62 ± 6	26/16	31.6 ± 4.8
Levelt et al. ³³	Controls	20	54 ± 10	9/11	28.6 ± 2.8	Elevated myocardial TG in T2D (1.13 ± 0.78 versus 0.64 ± 0.52, p = 0.017) Negative correlation between TG and systolic strain (r = −0.40, p = 0.003)
Levelt et al. ³³	T2D	46	55 ± 9	24/22	29.6 ± 5.7

BMI, body mass index; IGT, impaired glucose tolerance; TG, triglyceride; T2D, type 2 diabetes.