Fig. 5.

The concentration of RST in the chronic experiment. The concentrations of RST at 15, 30, and 45 minutes after drug injection in the chronic experiment were measured. A group (open circle, n = 7) and B group (cross mark, n = 7) were pre-treated with TJ by gavage for 7 days, whereas the C group (closed circle, n = 6) and D group (closed square, n = 5) were pre-treated with saline by gavage for 7 days. On the experiment day, the A and C groups were injected with RST alone, and B and D groups were injected with RST and TJ. Pre-treatment with TJ for 7 days reduced the blood concentration of RST when comparing the A and C groups. *P < 0.05 vs. C group. RST, rosuvastatin; TJ, tanjin.