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Bar graphs (mean ± standard error of the mean) depicting changes in mitochondrial functional measures of skeletal muscle (SM) myofibrillar mitochondria of normal and heart failure dogs. Depicted measures are maximum rate of ATP synthesis (top) and ATP/ADP ratio (bottom) after exposure to 0.01, 0.10, and 1.0 μM elamipretide. RLU = relative light units.
