Fig. 7.

Ginsenoside Rg3 (G-Rg3) inhibited the IgE-mediated PCA reaction. Anti-DNP-IgE (0.5 μg) was injected into the mouse dorsal skin 24 h before antigen challenge. DNP-BSA (1 μg) containing 1% Evans blue was injected by intravascular injection into the mouse tail vein (n = 6). G-Rg3, PDN (3 mg/kg), or saline was administered 1 h before the challenge with DNP-BSA. Dorsal skin was excised, and blue dye was dissolved in formaldehyde. Colorimetric changes were measured using a microplate reader at 620 nm. Results are the mean ± SD. *p < 0.05.

PCA, passive cutaneous anaphylaxis; PDN, prednisolone; SD, standard deviation.