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. 2019 Jan;22(1):3–16. doi: 10.22038/ijbms.2018.31776.7646

Figure 1.

Figure 1

The pathophysiological pathways that presumed to mediate polycystic ovary syndrome (PCOS) formation are expressed. Four different pathophysiological pathways lead to PCOS. Abbreviation: RFRP-3, arginine-phenylalanine-amide (RFamide) -related peptide 3; GnRH, gonadotropin releasing hormone; LH, luteinizing hormone; TNFα, tumor necrosis factor-α; IL-6, Interleukin-6