Figure 1.
The pathophysiological pathways that presumed to mediate polycystic ovary syndrome (PCOS) formation are expressed. Four different pathophysiological pathways lead to PCOS. Abbreviation: RFRP-3, arginine-phenylalanine-amide (RFamide) -related peptide 3; GnRH, gonadotropin releasing hormone; LH, luteinizing hormone; TNFα, tumor necrosis factor-α; IL-6, Interleukin-6