Table 1.

Effects of curcumin (CUR) and nanocurcumin (NCUR) treatment on biochemical parameters after induced toxicity by Diazinon (DZ) in rats. Data are presented as percentage of changes to the control group. Data are shown as mean ± SD (n=6).

Parameter	Control	DZ	CUR60	NCUR60	DZ+CUR25	DZ+CUR60	DZ+NCUR25	DZ+NCUR60
Urea(mg/dl)	100±7.92	140.2± 9.70 aaa	94.43± 8.46	88.56± 11.05	126.7±18.30	116.1± 16.57 b	103.8± 5.90	91.06±5.39 cc
Creatinin(mg/dl)	100± 22.61	317.6± 55.72 aa	205.4± 30.82	173± 62.22	193.5±30.55 b	194.6± 51.99 b	162.2±42.73 cc	104.9±16.70 ccc
ALT (U/L)	100 ± 15.24	185.8 ± 18.29 aaa	101.3 ± 18.47	96.76±12.61	166±11.13	149.8± 14.68	128.8 ±7.01	118.4±8.20 ccc , dd
AST (U/L)	100.0 ±8.31	165.7 ±9.14 aaa	96.95±6.74 bbb	97.48±6.93 bbb	119.9±5.36 bb	130.2±10.60 bbb	100.3±4.04 ccc , d	94.17±3.32 ccc , dd
ALP (U/L)	100.0± 8.28	149.0±7.36 aa	119.4±11.80	113.4±12.22	118.7±6.31	119.4±13.55	91.72±5.58 cc	97.46±9.47 cc
LDH (U/L)	100.0±10.31	194.1±30.59 aaa	105.4±9.37	109.1 ±3.82	163.7±23.07	99.15±8.42 bb	127.1±21.99 c	83.48±7.79 ccc , ee
CKMB(U/L)	100.0±19.62	297.7±63.10 aa	117.0±14.87	98.97± 16.56	241.8±55.49	213.7±33.73 b	168.8±14.49 cc	142.8±18.10 cc , dd
TroponinI(ng/ ml)	100.0 ±56.00	1359±344.1 aa	164.4± 57.82	183.0± 50.07	1130±127.2	1079±127.0	988.0±135.7	621.9±150.9 cc ,d

^aaaP<0.001 ,

^aaP<0.01 and

^ap<0.05 compared with the control group.

^bbbP<0.001,

^bbP<0.01,

^bP<0.05 compared with the DZ group.

^cccP<0.001 ,

^ccP<0.01,

^cp<0.05 compared with the CUR (25 mg/kg) group.

^ddP<0.01,

^dp<0.05 compared with the CUR (60 mg/kg) group.

^eeP<0.01,

^ep<0.05 compared with the NCUR(25 mg/kg) group.