Table 3.
The presence of non-sensitive isolates to colistin isolates carrying NDM-1 and other carbapenemase genes in CRPA isolates
| City/ Hospital | Gender | Sample/ward | carbapenemase genes |
aDLST type | bMHT | cMIC (mg/ml) CST | dMIC (mg/ml) IPM | eESBL | fMDR | Pattern antibiogram |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NDM-1 | VIM | IMP | KPC | GES | SPM | OXA-10 | IMP | MEM | ETP | TZP | CEP | AN | CST | CIP | GEN | CAZ | CTX | AZT | |||||||||
| Isfahan/ General | M | Urine/ ICU | + | - | + | - | - | - | + | 25-11 | + | 8 | ≥32 | + | + | R | R | R | I | R | R | R | R | R | R | R | R |
| Ahvaz/ General | M | Urine/ Urology | - | - | + | - | - | - | + | 25-11 | + | 32 | ≥32 | - | + | R | R | R | R | I | R | R | R | R | R | R | R |
| Ahvaz/ General | M | Blood/ ICU | + | + | - | - | - | - | + | 25-11 | + | 16 | ≥32 | - | + | R | R | R | R | I | R | R | R | R | R | R | R |
| Tehran/ General | F | Trachea/Women | - | - | - | - | - | - | + | 5-91 | + | 8 | ≥32 | - | + | R | R | R | R | R | R | R | R | R | R | R | R |
| Ahvaz/ General | F | Trachea/Women | - | - | - | - | - | - | + | null | + | 32 | 4 | - | - | I | I | R | S | R | S | R | R | S | R | S | S |
Resistance rate of non-sensitive isoleates to colistin P.aeruginosa to tested antibiotics imipenem (IPM), meropenem (MEM), ertapenem (ETP), piperacillin-tazobactam (TZP), cefepime (CFP), amikacin (AN), colistin (CST), ciprofloxacin (CIP), gentamicin (GEN), ceftazidime (CAZ), cefixime (CTX), aztreonam (AZT).
aDouble-locus sequence typing, bmodified hodge test, , cminimum inhibitory concentration of colistin, dminimum inhibitory concentration of imipenem, eextended-spectrum β-lactamases,fmulti-drug resistant.